GSE48350

Exploratory analysis

Select the exploratory analysis of interest by clicking on the tab.

CT: cortex, HP: hippocampus

Due to the large number of samples, the boxplots of the first 50 samples are shown. The distribution of counts is uniformly consistent across all samples.

 

Differential gene expression analysis

Comparison of brain samples by region: Alzheimer’s disease vs controls.

Summary

 

Study ID Region Total genes evaluated Significative genes Significative genes upregulated Significative genes downregulated
GSE48350 Cortex 22880 125 61 64
GSE48350 Hippocampus 22880 7948 6092 1856

Of note, upregulated genes are those with a positive logFC value (logFC > 0); meaning that they are more expressed in the Alzheimer’s disease condition. Downregulated genes are those with negative logFC value (logFC < 0); meaning that they are more expressed in the control condition.

 

Results at gene level

 

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