Overrepresentation analyses subset I
This functional characterisation has been carried out for the 179 significant genes of the “More repressed genes in Alzheimer’s disease females” subset (Subset I from the research article). They are genes downregulated in the SDID comparison (logFC < 0), meaning that are repressed in Alzheimer’s disease females compared to males; and downregulated in the IDF comparison (logFC < 0), meaning that are represesed in Alzheimer’s disease females compared to control females.
Significant results displayed.
Total evaluated genes: AACS, AASDHPPT, ACAD8, ADAM23, AMPH, ANO3, ARHGEF9, ARL8B, ATP6AP2, ATP6V1A, ATP6V1B2, ATP6V1C1, ATP6V1D, B4GALT6, BBS7, BEND6, BNIP3, BTBD10, BTRC, C11orf87, CAB39, CACNG3, CADPS, CALB1, CALY, CAMK1G, CAMK2A, CBLN2, CCDC3, CCDC6, CDC37L1, CDH12, CELSR2, COPS8, CPNE4, DCAF6, DLG3, DNAJA2, DNAJA4, EBP, EFNB3, EIF2S3, EIF4E3, ELMOD1, EPB41L3, EPDR1, FABP3, FAXC, FBXL16, FBXO28, FBXO33, FBXO34, FKBP1B, FRMPD4, GABRA1, GABRA5, GABRG2, GHITM, GLRB, GOT1, GPR137C, GPR22, GPRASP2, HLF, HOMER1, HSP90AB1, HTR1E, INA, INSIG2, ITPR1, JAZF1, KCND2, KCNJ6, KCNV1, KIF3C, KIFAP3, KLHL2, KLK7, KRT222, LAMP5, LGMN, LMBR1, LNX1, LOC441488, LRRC2, LRRC7, LRRC8B, LZTFL1, MADD, MAL2, MAP2, MAP2K1, MAP2K4, MAST3, MEF2C, MGST3, MMD, MPP1, MRAP2, MYH10, MYO5A, NBEA, NCAM2, NCDN, NCKAP1, NECAB1, NECAP1, NEDD4L, NETO2, NIPSNAP3B, NKRF, NLK, NRCAM, PACSIN1, PCMT1, PCSK2, PHF14, PIP4K2C, PLXNA2, PNMA1, PNMA2, PPM1E, PPP2R5D, PPP3CB, PPP3R1, PRICKLE2, PRKCB, PRNP, PRPS2, PRSS3, PTPRT, RAB39B, REEP1, REEP5, RGS4, RIC3, RIMS3, RSPO2, SCN4B, SEC23A, SEH1L, SELT, SEMA4F, SH3BGRL2, SH3GL2, SLBP, SLC30A3, SLITRK3, SLITRK4, SLITRK5, SNX10, SPATA2, SSX2IP, ST6GALNAC5, STAMBPL1, STEAP2, STK26, STMN3, SUSD4, TBC1D9, TBPL1, TBR1, TCERG1L, TERF2, TESPA1, THY1, TOLLIP, TOMM34, TUSC3, UBE2E2, UBE2T, UBE2W, UQCRC2, VPS35, VSNL1, VSTM2L, VTA1, ZNF189, ZNF385B.