GSE1297

Exploratory analysis

Select the exploratory analysis of interest by clicking on the tab.

HP: hippocampus

 

Differential gene expression analysis

Comparisons of hippocampus brain samples:

  • IDF: impact of Alzheimer’s disease in females (case female - control female).

  • IDM: impact of Alzheimer’s disease in males (case male - control male).

  • SDID: sex-based differential impact on Alzheimer’s disease [(case female - control female) - (case male - control male)].

Summary

 

Study ID Comparison Total genes evaluated Significative genes Significative genes upregulated Significative genes downregulated
GSE1297 IDF 13237 2 2 0
GSE1297 IDM 13237 0 0 0
GSE1297 SDID 13237 0 0 0

Of note, upregulated genes are those with a positive logFC value (logFC > 0); meaning that they are more expressed in the first condition of the comparison: for IDF and IDM, Alzheimer’s disease condition; for SDID Alzheimer’s disease females compared to males.

Downregulated genes are those with negative logFC value (logFC < 0); meaning that they are more expressed second condition of the comparison: for IDF and IDM, control condition; for SDID Alzheimer’s disease males compared to females.

 

Results at gene level

 

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