Descriptive Analysis Summary

Metaanalysis Options

Contrast Effect Model Functional Profiling Organism

(Premenopausal Women NASH – Premenopausal Women NAFL) -

(Men NASH – Men NAFL)

 Random Effect Model
  • Gene Set Analysis
  • Hipathia
 Homo sapiens

Sample Description

Study Premenopausal Women NASH Premenopausal Women NAFL Men NASH Men NAFL Total
gse48452 10 9 4 4 27
gse61260 10 7 12 12 41
gse66676 10 7 3 6 26
gse83452 35 32 46 6 119
gse89632 4 2 9 14 29
gse126868 6 4 9 12 31
gse130970 4 12 13 14 43

Sample Description Barplot

Differential Gene Expression Summary

Study Significant Genes UP Regulated DOWN Regulated Total Genes
gse48452 0 0 0 18832
gse61260 0 0 0 18832
gse66676 0 0 0 18832
gse83452 0 0 0 18832
gse89632 1 0 1 18832
gse126868 0 0 0 13904
gse130970 0 0 0 16657

Differential Pathway Signaling Summary

Study Significant Genes UP Regulated DOWN Regulated Total Genes
gse48452 0 0 0 1876
gse61260 0 0 0 1876
gse66676 0 0 0 1876
gse83452 20 16 4 1876
gse89632 0 0 0 1876
gse126868 0 0 0 1876
gse130970 0 0 0 1876

Gene Set Analysis Summary

Study Significant Functions UP Regulated DOWN Regulated Total Functions
gse48452 808 166 642 7798
gse61260 284 249 35 7798
gse66676 889 721 168 7798
gse83452 1021 90 931 6585
gse89632 119 52 67 7930
gse126868 1318 1168 150 7255
gse130970 1651 1244 407 7595

Hipathia Summary

Study Significant Pathways UP Regulated DOWN Regulated Total Pathways
gse48452 27 5 22 229
gse61260 11 5 6 229
gse66676 32 2 30 229
gse83452 27 2 25 228
gse89632 3 2 1 229
gse126868 60 55 5 229
gse130970 51 31 20 229

Meta-Analysis Summary

Analysis Tool Significant Functions UP Regulated DOWN Regulated
Gene Set Analysis 9 6 3
Hipathia 4 4 0