Unveiling Sex-based Differences in Multiple Transcriptomic Studies through Comprehensive Functional Meta-analysis
While sex-based differences in various health scenarios have been thoroughly acknowledged in the literature, we lack a deep analysis of sex as a variable in this context. To fill this knowledge gap, we created MetaFun as an easy-to-use web-based tool to meta-analyze multiple transcriptomic datasets with a sex-based perspective to gain major statistical power and biological soundness. Furthermore, MetaFun can be used to perform case-control meta-analyses, allowing researchers with basic programming skills to access this methodology. ↗
The Principe Felipe Research Center (CIPF), with the joint financing of the European Union through the Operativa Program of the European Regional Development Fund (ERDF/FEDER) of the Comunitat Valenciana 2014-2020, has improved its Computer Centre with the remodeling of the computing facilities and the acquisition of new servers and computing infrastructures.
Currently, the computer cluster is made of 44 computer nodes, with up to 600 CPU‘s and an accumulated RAM memory of 11 TeraBytes. It uses a distributed file storage system called Lustre, which counts on a capacity of 1 PetaByte, with the capacity to storage and analyze data coming from biomedical projects.
The Computational Biomedicine Lab is responsible for the administration and maintenance of the new computer cluster located at the Principe Felipe Research Center.
Use of the Cluster
The new CIPF cluster, as stated in the agreement between the Conselleria de Sanitat Universal i Salut Pública of the Generalitat Valenciana and the CIPF, is a public resource devoted to the storage and analysis of data coming from:
- Precision medicine data.
- Biomedical data.
The use of the cluster is open to public institutions and research groups in the Comunitat Valenciana working in biomedical fields, within the frame approved by the previously mentioned agreement. If you are interested in using the cluster, please contact us for further information.