Table of Contents
Day 1
11:00 – 11:15 Registration
11:15 – 11:45 Welcome, course overview and networking
Francisco García García
11:45 – 13:00 Introduction
Marta Hidalgo García
13:00 – 14:30 Lunch break
Will be held in the cafeteria of the CIPF.
14:30 – 16:00 Omics-based biomarkers detection I
Francisco García García
- Tool: Babelomics (http://babelomics.bioinfo.cipf.es/ from Firefox browser)
16:00 – 16:15 Coffee break
16:15 – 18:00 Visualization of omics data
José F. Català Senent
- Tools:
- BoxPlotR (http://boxplot.tyerslab.com)
- Heatmapper (http://heatmapper.ca)
Day 2
9:30 – 11:00 Omics-based biomarkers detection II
Francisco García García
- Tool: Babelomics (http://babelomics.bioinfo.cipf.es/ from Firefox browser)
11:00 – 11:30 Coffee break
11:30 – 13:00 Prioritization of genes
Sandra Alandes Esteve
13:00 – 14:30 Lunch break
Will be held in the cafeteria of the CIPF.
14:30 – 16:00 Functional profiling: over-representation and GSEA methods
Francisco García García
- Tools:
- Babelomics (http://babelomics.bioinfo.cipf.es/ from Firefox browser)
16:00 – 16:15 Coffee break
16:15 – 18:00 Functional profiling: protein-protein interaction
Francisco García García
Day 3
9:30 – 11:00 Single-cell analysis
Antonio Jordán Pla
11:00 – 11:30 Coffee break
11:30 – 13:00 Working with your data
Marta Hidalgo, Francisco García, José F. Català, Sandra Alandes, Antonio Jordán
- During this session you can analyze your data with us.
- You can also do the exercises of other sessions.
- If you do not have any data, this will not be a problem and here we have a full practice for you.
13:00 – 13:15 Course feedback and wrap up
Francisco García García, fgarcia@cipf.es
References and links
- High throughput estimation of functional cell activities reveals disease mechanisms and predicts relevant clinical outcomes. Hidalgo MR, Cubuk C, Amadoz A, Salavert F, Carbonell-Caballero J, Dopazo J. Oncotarget. 2017;8(3):5160-5178
- Integrated gene set analysis for microRNA studies. Garcia-Garcia F, Panadero J, Dopazo J, Montaner D. Bioinformatics. 2016 Sep 15;32(18):2809-16. doi: 10.1093/bioinformatics/btw334. Epub 2016 Jun 20. PMID: 27324197
- Actionable pathways: interactive discovery of therapeutic targets using signaling pathway models. Salavert F, Hidago MR, Amadoz A, Çubuk C, Medina I, Crespo D, Carbonell-Caballero J, Dopazo J. Nucleic Acids Res. 2016;44:W212-W216
- Babelomics 5.0: functional interpretation for new generations of genomic data. Alonso R, Salavert F, Garcia-Garcia F, et al. Nucleic Acids Res. 2015;43:W117-W121.
- Assessing the impact of mutations found in next generation sequencing data over human signaling pathways. Hernansaiz-Ballesteros RD, Salavert F, Sebastián-León P, Alemán A, Medina I, Dopazo J. Nucleic Acids Res. 2015;43:W270-W275.
- Understanding disease mechanisms with models of signaling pathway activities. Sebastian-Leon P, Vidal E, Minguez P, et al. BMC Syst Biol. 2014;8(1):121.
- Inferring the functional effect of gene expression changes in signaling pathways. Sebastián-León P, Carbonell J, Salavert F, Sanchez R, Medina I, Dopazo J. Nucleic Acids Res. 2013;41:W213-W217.
- A web-based interactive framework to assist in the prioritization of disease candidate genes in whole-exome sequencing studies. Alemán A, Garcia-Garcia F, Salavert F, Medina I, Dopazo J. Nucleic Acids Res. 2014;42:W88-W93.
- A web tool for the design and management of panels of genes for targeted enrichment and massive sequencing for clinical applications. Alemán A, Garcia-Garcia F, Medina I, Dopazo J. Nucleic Acids Res. 2014;42:W83-W87.
- SNOW, a web-based tool for the statistical analysis of protein-protein interaction networks. Minguez P, Gotz S, Montaner D, Al-Shahrour F, Dopazo J. Nucl. Acids Res. 2009;37:W109-114
- Genome Maps, a new generation genome browser. Medina I, Salavert F, Sanchez R, et al. Nucleic Acids Res. 2013;41:W41-W46.
- Heatmapper: web-enabled heat mapping for all. Babicki S, Arndt D, Marcu A, el al. Nucleic Acids Res. 2016;44:W147-W153
- 40 years of boxplots. Wickman H & Stryjewski L. http://vita.had.co.nz/papers/boxplots.pdf