Descriptive Analysis Summary

General Options

Organism Homo sapiens
Tissues Blood
Nervous cells
Performed Contrasts Alias Comparison
SDID comparison (Female Case - Female Control) - (Male Case - Male Control)
IDF comparison Female Case - Female Control
IDM comparison Male Case - Male Control
Number of studies Tissue N
Blood 5
Nervous 4
TOTAL 9

Sample Class Summary

Study Multiple sclerosis Female Multiple sclerosis Male Control Female Control Male Total
GSE37750 7 2 6 2 17
GSE41848 41 13 28 10 92
GSE41849 12 9 13 9 43
GSE41890 6 8 12 12 38
GSE62584 16 8 20 16 60
GSE108000 22 8 7 3 40
GSE111972 5 10 9 7 31
GSE131281 58 6 11 31 106
GSE135511 22 18 3 4 47

Differential Expression Summary

Study SDID comparison IDF comparison IDM comparison Total Genes
Significant LFC > 0 LFC < 0 Significant LFC > 0 LFC < 0 Significant LFC > 0 LFC < 0
GSE37750 0 0 0 0 0 0 0 0 0 22899
GSE41848 0 0 0 32 23 9 0 0 0 17479
GSE41849 0 0 0 0 0 0 0 0 0 17479
GSE41890 30 15 15 21 17 4 96 93 3 19914
GSE62584 501 145 356 0 0 0 80 55 25 13277
GSE108000 384 154 230 5152 2038 3114 4020 1811 2209 21586
GSE111972 0 0 0 0 0 0 0 0 0 20846
GSE131281 4 4 0 23 15 8 3 0 3 20923
GSE135511 0 0 0 12 12 0 214 100 114 15434

Gene Meta-Analysis Options

Contrast Effect Model Organism Tissue
SDID comparison Random Effect Model Homo sapiens Blood, Nervous & All tissues
IDF comparison Random Effect Model Homo sapiens Blood, Nervous & All tissues
IDM comparison Random Effect Model Homo sapiens Blood, Nervous & All tissues

Gene Meta-Analysis Summary

Tissue SDID comparison IDF comparison IDM comparison Genes
Significant LOR > 0 LOR < 0 Significant LOR > 0 LOR < 0 Significant LOR > 0 LOR < 0
Blood 1 1 0 9 5 4 32 27 5 21190
Nervous 13 7 6 90 33 57 72 29 43 20937
Both tissues 1 1 0 11 7 4 15 8 7 23200

Upset plots

Blood Nervous Both tissues

Gene Set Analysis Summary (Nervous tissue)

Ontology SDID comparison IDF comparison IDM comparison
Significant LOR > 0 LOR < 0 Significant LOR > 0 LOR < 0 Significant LOR > 0 LOR < 0
Biological Process (BP) 0 0 0 272 228 44 316 282 34
KEGG Pathways 1 1 0 29 20 9 26 17 9