Welcome


Biomedicine can only be understood in the context of genomics and with the concourse of bioinformatics. Our department aims to tackle biomedical problems from a system's biology perspective. Following this, the general objective we seek through the main lines of research is to relate mutations to their effect at both cellular and phenotypic level trying to understand the underlying mechanism of action.

 

Systems Genomics

 

Genes operate within an intricate network of interactions that we have only recently started to envisage.  Many higher-order levels of interaction are continuously being discovered. In this scenario we are interested in developing methods and tools which can help to understand large-scale experiments from a systems biology perspective.

 

 

Genomics of Gene Expression 

Our research focusses on the dynamics and functional aspects of gene expression on the genome scale. We develop statistical approaches for the analysis of multifactorial and time-course gene expression data, focussing on their integration with functional and phenotipic data. Currently, we use Next Generation Sequencing methodologies to analyze the relationship between gene expression and genomics features. We strive to generate user-friendly tools that can routinely be use in experimental labs.

 

Computational Biology

 

We are focused on the developement of advance computing solutions to solve issues in genomic data analysis. We are intereseted in developing algorithms, databases and tools for the analysis of genomic data that enable researchers to understand what biological processes or variants are involved in different phenotypes or diseases. Our main lines of reasearch cover among others genomic variant analysis, machine learning, NGS analysis or cloud-based solutions for Big Data.

 

 

Bioimaging Lab

 

Center for Excellence and Technologic Innovation in Bioimaging -in Spanish "Centro de Excelencia e Innovación Tecnológica de Bioimagen (CIPF-CEIB) – is the result of collaboration between Valencian Health Service (AVS) and Prince Felipe Research Centre (CIPF). CIPF-CEIB is a digital bioimaging bank that provides its knowledge to added value services for the Electronic Patient History Information System in charge of the Public Health System in our region. This Centre of Excellence is focused on Medical Digital Imaging and its main concern relates to researching and developing in quantitative and qualitative aspects of the Medical Imaging. This includes assistance support, management and development of new programs, technological proposals and innovation related to medical imaging. The main goal of CIPF-CEIB is to implement all these tools in sanitary centres to improve the assistance process and promoting the multidisciplinary approach in different areas, such as diagnostic imaging, radiotherapy, and biochemical technologies, related with bioimaging.