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rma [2010/09/29 13:00]
mbleda
rma [2010/09/29 15:37]
mbleda
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 **RMA** ([[http://​biostatistics.oxfordjournals.org/​cgi/​content/​abstract/​4/​2/​249|"​Robust Multi-Array"​]]) background correction is followed by a [[http://​bioinformatics.oxfordjournals.org/​cgi/​content/​abstract/​19/​2/​185|"​quantile"​]] scale transformation to get similar intensity distribution across arrays. **RMA** ([[http://​biostatistics.oxfordjournals.org/​cgi/​content/​abstract/​4/​2/​249|"​Robust Multi-Array"​]]) background correction is followed by a [[http://​bioinformatics.oxfordjournals.org/​cgi/​content/​abstract/​19/​2/​185|"​quantile"​]] scale transformation to get similar intensity distribution across arrays.
  
-Only **PM** ​(Partial Match) probes are used in the computation (**MM** ​(MissMatch) **probes are discarded**) and [[http://​en.wikipedia.org/​wiki/​Median_polish|"​median polish"​]] is used to summarize probe-sets into a unique intensity measuremen. RMA returns normalized data in **log2** scale, as in the original RMA implementation.+Only Perfect Match (**PM**) probes are used in the computation ​Missmatch ​(**MM**) **probes are discarded**) and [[http://​en.wikipedia.org/​wiki/​Median_polish|"​median polish"​]] is used to summarize probe-sets into a unique intensity measuremen. RMA returns normalized data in **log2** scale, as in the original RMA implementation.
rma.txt ยท Last modified: 2010/09/29 15:38 by mbleda
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