• For the Reactome analysis, the results are divided by cell type and direction of the results (up,down). While the colour of the dot is determined by an adj p.value < 0.05, and the dot size is determined by the absolute LOR (logarithm 2 odds ratio in absolute value) (a larger size implies a larger absolute LOR, i.e. a larger overrepresentation of this pathway).

• For the Gene Ontology analysis, the results are divided by cell type and direction of the results (up,down). While the dot colour is determined based on a p.value < 0.05, and the dot size is determined by the -log10(p.value) (a larger size implies a more significant p-value).