New Pupasuite 2 release

A new Pupasuite 2 release has been recently published. It includes a collection of new improvements that covers both web interface and inner functionalities.

PupaSuite is an interactive web-based SNP analysis tool that allows for the selection of relevant SNPs within a gene, based on different characteristics of the SNP itself, such as validation status, type, frequency/population data and putative functional properties (pathological SNPs, SNPs disrupting potential transcription factor binding sites, intron/exon boundaries…). Also, PupaSuite provides information about LD parameters (based on genotype data from HapMap) and identifies haplotype blocks and tag SNPs (using the Haploview software)

PupaSuite was created to join PupaSNP & PupasView in a single, integrated suite, to improve their functionality and to implement new facilities such as the analysis of user's data to derive haplotypes with functional information. A new estimator of putative effect of polymorphisms has been included that uses evolutionary information. Also SNPeffect database predictions have been included.

PupaSuite operates with a collection of entries of dbSNP mapped to the Golden Path genome assembly, as implemented in human section of Ensembl (Hubbard T. et al, 2005).

You can found the new releas at http://pupasuite.bioinfo.cipf.es.