FatiGO: a web tool for finding significant associations of Gene Ontology terms with groups of genes

TitleFatiGO: a web tool for finding significant associations of Gene Ontology terms with groups of genes
Publication TypeJournal Article
Year of Publication2004
AuthorsAl-Shahrour F, Diaz-Uriarte R, Dopazo J
Journal TitleBioinformatics
Volume20
Issue4
Pages578-80
Keywords*Algorithms Artificial Intelligence Databases, babelomics, DNA/*methods *Software, Genetic Gene Expression Profiling/*methods *Hypermedia Information Storage and Retrieval/*methods *Internet *Phylogeny Sequence Alignment/methods Sequence Analysis
Abstract

We present a simple but powerful procedure to extract Gene Ontology (GO) terms that are significantly over- or under-represented in sets of genes within the context of a genome-scale experiment (DNA microarray, proteomics, etc.). Said procedure has been implemented as a web application, FatiGO, allowing for easy and interactive querying. FatiGO, which takes the multiple-testing nature of statistical contrast into account, currently includes GO associations for diverse organisms (human, mouse, fly, worm and yeast) and the TrEMBL/Swissprot GOAnnotations@EBI correspondences from the European Bioinformatics Institute.

URLhttp://bioinformatics.oxfordjournals.org/content/20/4/578.abstract