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Next Generation Sequencing Data Analysis
Next-Generation Sequencing (NGS) technologies offer novel and rapid ways for genome-wide characterisation and profiling of mRNAs, small RNAs, transcription factor regions, structure of chromatin and DNA methylation patterns, microbiology and metagenomics.
There has never been more potentially available information to study biological systems like cells, organs, or patients. However, it is a non-trivial task to transform the vast amount of biomedical data into useful information supporting scientific progress and/or patient management.
What is this course for?
This course is a hands-on course for the analysis of genomics/transcriptomics Next Generation Sequencing data. We provide an introduction to NGS technologies and its applications to focus on genomic variant discovery and trancriptomic studies.
The first part of the course reviews the different NGS technologies and their applications as well as the computational requirements needed by NGS-based projects. Following this introduction to NGS, participants will learn about NGS data quality, data pre-processing, how to compare sequenced reads with a reference genome and how to visualize the results in a genomic context. Then, the main aspects of genomic variant detection and annotation will be covered. The last part of the course will be devoted to transcriptomic studies (RNA-seq and miRNA-seq), where participants will learn to quantify genomic expression, determine differential expression, detect isoforms, discover new miRNAs, etc.
By the end of the course, participants will have acquired skills to interpret NGS data and to use multiple software tools for genetic variant detection and for trasncriptomics studies.
Who is the target audience?
The course is oriented to experimental researchers, post-doctoral and PhD students in the field of Molecular Biology, Biotechnology, Biomedicine, Bioinformatics and related disciplines who want to be initiated on Next Generation Sequencing data analysis.
The course will be taught in English, unless ALL the participants are Spanish speakers, in which case it will be taught in Spanish
Why attending this course?
NGS technologies are greatly contributing to the development of omics studies. Nevertheless, it is a non-trivial task to transform the vast amount of data obtained with high-throughput sequencers into useful information. Thus, NGS data analysis is still a major bottleneck for most researchers in this field. The ability of correctly interpreting NGS results, as well as knowledge on the intrinsic properties of these data are essential to avoid incorrect experimental designs and the application of inappropriate analysis methodologies. The aim of this course is to familiarise researchers with NGS data and to initiate them on the analysis pipeline by providing hands-on training on analytical methodologies.
Who organizes this course?
This course is organized by the Genomics and Bioinformatics Platform of Andalusia (GBPA) in collaboration with BULL.
Will be held from October 2nd to the 4th, 2013.
For more information follow this link: INFORMATION ON THE COURSE
Pre-registration until July 17th, 2013 (included).
Notification of acceptance July 24th, 2013.
Registration and payment from July 25th to September 16th, 2013 (both included).
The Genomics and Bioinformatics Platform of Andalusia (GBPA)
C/Albert Einstein Street
Cartuja 93 Scientific and Technology Park
For any query related to the course, send an e-mail to course at gbpa.es or contact the Centre Secretary by telephone (+34 955 402 240)
Wed, 02/10/2013 (All day) - Fri, 04/10/2013 (All day)
The Genomics and Bioinformatics Platform of Andalusia (GBPA), Sevilla, Spain